Proposed/Planning
1. ISCHEMIA-Heart Failure Planning Study
ISCHEMIA-Heart Failure Planning Study UPDATE
Drs. Judith Hochman, Sripal Bangalore, John Spertus, and Stuart Katz are pleased to provide an update on the ISCHEMIA-Heart Failure Planning Study funded by NHLBI (R34 HL14 1621-01A1). All the planned questionnaires of the planning study have now been completed, including site surveys, screening logs, physician and patient surveys. Based on preliminary analysis of the data, there is consistent evidence to support study feasibility and enthusiasm for the potential importance of the study on clinical practice. As an example, we have included the response from our Clinician Survey regarding the following question: Does the proposed clinical trial to compared CABG vs. PCI address an important gap in knowledge?
95.7% of the 303 respondents indicated “Yes." Analysis of physician survey and patient survey responses are ongoing. Additional updates will be provided as new data become available.
- The ISCHEMIA Coordinating Center at NYU is currently planning for a new study! Drs. Stuart Katz, Judith Hochman, and Sripal Bangalore are pleased to introduce the ISCHEMIA-Heart Failure planning study funded by NHLBI (R34 HL141621-01A1). This study will explore the feasibility of conducting a future randomized clinical trial to evaluate revascularization strategies in patients with ischemic cardiomyopathy and reduced left ventricular ejection fraction.
- Who will be asked to participate? ISCHEMIA sites that have reported onsite PCI and CABG capabilities. Are opportunities available to contribute to the proposed trial? Pilot data are currently being collected through various methods, such as interviews and surveys, and from a variety of sources, including industry experts, ISCHEMIA sites, and patients. We may reach out to your site to participate in the collection of pilot data as these opportunities arise. How will we use the pilot data? All pilot data collected will be used to optimize study design for a future international multisite clinical trial to compare the effects of myocardial revascularization with coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI) on clinical outcomes in patients with ischemic cardiomyopathy with reduced ejection fraction. Interested in learning more? Please contact us at ISCHEMIA-HF@nyulangone.org to learn more about this exciting pilot study.