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4000th ISCHEMIA Trial Randomization!


We are delighted to announce that the 4000th ISCHEMIA Trial participant has been randomized!

A huge congratulations to all of the site teams for their extraordinary work and ongoing dedication.  As this landmark study approaches its sixth and final year of enrollment, we need your extra effort more than ever.

We look forward ot your continued contributions to the trial as we aim to surpass our minimal goal of 5000 randomizations.  It is an honor to be part of this endeavor, and we hope you feel the same!


Kind regards,

Judy and David


What is the ISCHEMIA Study? 

  • An international comparative effectiveness study
  • The purpose of ISCHEMIA is to determine the best way to manage stable ischemic heart disease
  • Patients with moderate or severe ischemia on stress test imaging may be eligible for participation

If you are a physician and would like more information, please visit the For Physicians section. If you are a patient and would like to learn more about the ISCHEMIA study, please e-mail ischemia@nyumc.org 

Why is the ISCHEMIA Study Important?

Ischemic heart disease (IHD) is the leading cause of death and disability worldwide and affects 17,600,000 Americans, resulting in about 450,000 deaths in the United States annually. Globally, 7.2 million deaths are caused by IHD each year.

Medical therapy (medication and lifestyle changes) should always be used to treat IHD. Many doctors routinely use an invasive approach in addition to medical therapy to treat IHD; however, it is not known if this approach is better than medical therapy alone as the initial treatment of patients with stable ischemic heart disease (SIHD). ISCHEMIA is designed to find the answer. Click here to learn more about the ISCHEMIA study.

Make A Difference In Heart Health - Women in Clinical Trials

Heart disease is the leading cause of death for women.  Visit the Women in Clinical Trials webpage to learn more about how you can make a difference. 

ISCHEMIA Enrollment Updates

ISCHEMIA Enrollment Updates

As of March 22nd 2017, there are 4,009 participants (pts) randomized worldwide in the ISCHEMIA study. Click here to see the randomizations by country.

Congratulations To Our Top Sites!

Site name Region Study Team Rand Rate & Total Rands
Government Medical College India PI: Dr. Sajeev, Dr. Rajesh & Dr. Kumar SC: Anand & Bijith

168 pts,
4.2 pts/mth

Northwick Park Hospital- Royal Brompton Hospital, London U.K PI: Senior SC:Kinsey, Collins, Gurunathan, Hassan, Howard, Kabalakkat & Evans

165 pts,
3.5 pts/mth

Sri Jayadeva Institute of Cardiovascular Sciences and Research, Banglore-Karnataka India PI: Dr. Manjunath & Dr. Moorthy SC: Nataraj& Murthy

116 pts,
3.0 pts/mth

Coronary and Structual Heart Diseases Department, Institute of Cardiology, Warsaw Poland PI: Prof. Demkow SC: Chojnacka, Freleck & Pracon

109 pts,

Atlanta V.A. Medical Center USA PI: Dr. Mavromatis SC: Montazeri, Lee & Doan 108 pts,
2.6 pts/mth
Heart Instituto do Coracao- University of Sao Paulo Brazil PI: Dr. Hueb SC: Takiuti 107 pts,
3.4 pts/mth
Hospital Universitario La Paz Spain PI: Dr. Lopez Sendon SC: Valbuena, Castro, La Paz Mediavilla, Valbuena & Fernandez-Figar  96 pts,
2.3 pts/mth
Bakulev Scientific Center for Cardiovascular Surgery Russia PI: Dr. L. Bockeria SC: O. Bockeria, & Kudzoeva  89 pts,
2.1 pts/mth
Instituto Dante Pazzanese de Cardiologia Brazil PI: Dr. Pauloa Smanio SC: Leonardo De Pizzol A. Caetano  70 pts,
2.1 pts/mth
Ram Manohar Lohia Hospital India PI: Dr. Pandit SC: Bajaj & Yadav  70 pts,
1.7 pts/mth