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What is the ISCHEMIA Study? 

  • An international comparative effectiveness study
  • The purpose of ISCHEMIA is to determine the best way to manage stable ischemic heart disease
  • Patients with moderate or severe ischemia on stress test imaging may be eligible for participation

If you are a physician and would like more information, please visit the For Physicians section. If you are a patient and would like to learn more about the ISCHEMIA study, please e-mail ischemia@nyumc.org 

Why is the ISCHEMIA Study Important?

Ischemic heart disease (IHD) is the leading cause of death and disability worldwide and affects 17,600,000 Americans, resulting in about 450,000 deaths in the United States annually. Globally, 7.2 million deaths are caused by IHD each year.

Medical therapy (medication and lifestyle changes) should always be used to treat IHD. Many doctors routinely use an invasive approach in addition to medical therapy to treat IHD; however, it is not known if this approach is better than medical therapy alone as the initial treatment of patients with stable ischemic heart disease (SIHD). ISCHEMIA is designed to find the answer. Click here to learn more about the ISCHEMIA study.

Make A Difference In Heart Health - Women in Clinical Trials

Heart disease is the leading cause of death for women.  Visit the Women in Clinical Trials webpage to learn more about how you can make a difference. 

ISCHEMIA Enrollment Updates

ISCHEMIA Enrollment Updates

As of April 24th 2017, there are 4,147 participants (pts) randomized worldwide in the ISCHEMIA study. Click here to see the randomizations by country.

Congratulations To Our Top Sites!

Site name Region Study Team Rand Rate & Total Rands
Government Medical College India PI: Dr. Sajeev, Dr. Rajesh & Dr. Kumar SC: Anand & Bijith

172 pts,
4.2 pts/mth

Northwick Park Hospital- Royal Brompton Hospital, London U.K PI: Senior SC:Kinsey, Collins, Gurunathan, Hassan, Howard, Kabalakkat & Evans

168 pts,
3.5 pts/mth

Sri Jayadeva Institute of Cardiovascular Sciences and Research, Banglore-Karnataka India PI: Dr. Manjunath & Dr. Moorthy SC: Nataraj& Murthy

128 pts,
3.2 pts/mth

Heart Instituto de Coracao- University of Sao Paulo Brazil PI: Dr. Hueb SC: Takiuti

111 pts,

3.4 pts/mth

Atlanta V.A Medical Center USA PI: Dr. Mavromatis SC: Montazeri, Lee & Doan 111 pts,
2.6 pts/mth
Coronary and Structural Heart Diseases Department, Institute of Cardiology, Warsaw Poland PI: Prof. Demkow SC: Chojnacka, Freleck & Pracon 110 pts,
2.2 pts/mth
Hospital Universitario La Paz Spain PI: Dr. Lopez Sendon SC: Valbuena, Castro, La Paz Mediavilla, Valbuena & Fernandez-Figar  99 pts,
2.3 pts/mth
Bakulev Scientific Center for Cardiovascular Surgery Russia PI: Dr. L. Bockeria SC: O. Bockeria, & Kudzoeva  93 pts,
2.2 pts/mth
Instituto Dante Pazzanese de Cardiologia Brazil PI: Dr. Pauloa Smanio SC: Leonardo De Pizzol A. Caetano  73 pts,
2.2 pts/mth
Ram Manohar Lohia Hospital India PI: Dr. Neeraj Pandit SC: Sheromani, Neeraj, & Yadav  72 pts,
1.7 pts/mth